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Tdark
TTC23L
Tetratricopeptide repeat protein 23-like

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000502674
  • ENSP00000425242
  • ENSG00000205838
  • ENST00000505624
  • ENSP00000422188
  • ENST00000610313
  • ENSP00000484792

Symbol
  • MC25-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.77
histone modification site profile
0.74
tissue sample
0.69
cell line
0.61
gene perturbation
0.59


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.16   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 64   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.16   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 64   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urinary metabolite measurement
1
2
2
89.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urinary metabolite measurement
2
89.9
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tetratricopeptide repeat domain 23 like
VGNC:7192
461929
Macaque
tetratricopeptide repeat domain 23 like
703035
Mouse
MGI:1923027
75777
Dog
tetratricopeptide repeat domain 23 like
VGNC:47945
479367
Horse
tetratricopeptide repeat domain 23 like [Source:HGNC Symbol;Acc:HGNC:26355]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tetratricopeptide repeat domain 23 like
Macaque
tetratricopeptide repeat domain 23 like
Mouse
Dog
tetratricopeptide repeat domain 23 like
Horse
tetratricopeptide repeat domain 23 like [Source:HGNC Symbol;Acc:HGNC:26355]
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6PF05-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (5)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (6)
1 – 6 of 6
IQCE
Tdark
Novelty:  0.24800472
p_int:  0.999999732
p_ni:  1.32e-7
p_wrong:  1.36e-7
Score:  0.485
Data Source:  BioPlex,STRINGDB
EFCAB7
Tdark
Novelty:  0.36952617
p_int:  0.99999805
p_ni:  0.000001914
p_wrong:  3.5e-8
Score:  0.534
Data Source:  BioPlex,STRINGDB
VASP
Tbio
Novelty:  0.00041984
p_int:  0.999989867
p_ni:  0.000010133
Score:  0.234
Data Source:  BioPlex,STRINGDB
CTAGE5
Tbio
Novelty:  0.04516631
Score:  0.686
Data Source:  STRINGDB
PLK4
Tchem
Family:  Kinase
Novelty:  0.00265851
Score:  0.456
Data Source:  STRINGDB
RAD21
Tbio
Novelty:  0.00270936
Score:  0.415
Data Source:  STRINGDB
Publication Statistics
PubMed Score  3.16

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer