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Tdark
SPAG11A
Sperm-associated antigen 11A

Protein Summary
Description
May have antimicrobial activity. May also play a role sperm maturation, storage, and protection.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000351436
  • ENSP00000297496
  • ENSG00000178287

Symbol
  • EP2
  • HE2
  • HE2
  • EDDM2A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.73
cell line
0.56
gene perturbation
0.55
cellular component
0.53
disease
0.51


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.29   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 69   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.29   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 69   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (8)
1 – 8 of 8
SPAG11B
Tbio
Novelty: 0.11942279
p_int: 0.999999921
p_wrong: 7.9e-8
Data Source: BioPlex
DEFB4A
Tbio
Novelty: 0.00211237
Score: 0.742
Data Source: STRINGDB
TRIM64
Tdark
Score: 0.587
Data Source: STRINGDB
EEF1AKMT1
Tdark
Family: Enzyme
Novelty: 0.42857143
Score: 0.53
Data Source: STRINGDB
SRC
Tclin
Family: Kinase
Novelty: 0.00009742
Score: 0.505
Data Source: STRINGDB
DEFB119
Tbio
Novelty: 0.73170732
Score: 0.5
Data Source: STRINGDB
CST11
Tbio
Novelty: 0.08527919
Score: 0.435
Data Source: STRINGDB
EPPIN
Tbio
Novelty: 0.03159337
Score: 0.422
Data Source: STRINGDB
Publication Statistics
PubMed Score  3.29

PubMed score by year
PubTator Score  77.75

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer