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Tbio
PGM2L1
Glucose 1,6-bisphosphate synthase

Protein Summary
Description
Glucose 1,6-bisphosphate synthase using 1,3-bisphosphoglycerate as a phosphate donor and a series of 1-phosphate sugars as acceptors, including glucose 1-phosphate, mannose 1-phosphate, ribose 1-phosphate and deoxyribose 1-phosphate. 5 or 6-phosphosugars are bad substrates, with the exception of glucose 6-phosphate. Also synthesizes ribose 1,5-bisphosphate. Has only low phosphopentomutase and phosphoglucomutase activities.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000298198
  • ENSP00000298198
  • ENSG00000165434

Symbol
  • BM32A
  • BM32A
  • PMMLP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.91
transcription factor perturbation
0.84
transcription factor binding site profile
0.78
protein domain
0.73
microRNA
0.72


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.06   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 117   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.06   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 117   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (57)
PGM1
Tbio
Family:  Enzyme
Novelty:  0.00163947
Score:  0.959
Data Source:  STRINGDB
UGP2
Tbio
Family:  Enzyme
Novelty:  0.00760963
Score:  0.945
Data Source:  STRINGDB
PYGL
Tchem
Family:  Enzyme
Novelty:  0.01157477
Score:  0.94
Data Source:  STRINGDB
PYGB
Tchem
Family:  Enzyme
Novelty:  0.00224148
Score:  0.923
Data Source:  STRINGDB
PYGM
Tchem
Family:  Enzyme
Novelty:  0.00507768
Score:  0.922
Data Source:  STRINGDB
AGL
Tbio
Novelty:  0.00166875
Score:  0.914
Data Source:  STRINGDB
PGM2
Tbio
Family:  Enzyme
Novelty:  0.00922421
Score:  0.904
Data Source:  STRINGDB
ENPP3
Tchem
Family:  Enzyme
Novelty:  0.00414129
Score:  0.903
Data Source:  STRINGDB
ENPP1
Tchem
Family:  Enzyme
Novelty:  0.00256132
Score:  0.903
Data Source:  STRINGDB
UPP1
Tchem
Family:  Enzyme
Novelty:  0.01384975
Score:  0.84
Data Source:  STRINGDB
Nearest Tclin Targets (3)
Explore Nearest Tclin Targets
1 – 3 of 3
AMY2A
Tclin
Family:  Enzyme
KEGG Distance:  4
Common Pathways:  2
MGAM
Tclin
Family:  Enzyme
KEGG Distance:  4
Common Pathways:  2
GAA
Tclin
Family:  Enzyme
KEGG Distance:  4
Common Pathways:  2
Pathways (10)
Galactose catabolism (R-HSA-70370)

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Find Similar Targets
Items per page:
1 – 5 of 8
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Galactose catabolism
Reactome
Glucose metabolism
Reactome
Glycogen breakdown (glycogenolysis)
Reactome
Glycogen metabolism
Reactome
Glycogen synthesis
Name
Explore in Pharos
Explore in Source
Galactose catabolism
Glucose metabolism
Glycogen breakdown (glycogenolysis)
Glycogen metabolism
Glycogen synthesis
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
1
1
12.2
hemoglobin measurement
1
1
1
7.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
12.2
hemoglobin measurement
1
7.2
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
phosphoglucomutase 2 like 1
VGNC:13320
451420
Macaque
phosphoglucomutase 2 like 1
718887
Mouse
MGI:1918224
70974
Rat
RGD:1583226
685076
Dog
phosphoglucomutase 2 like 1
VGNC:44465
485198
Species
Name
OMA
EggNOG
Inparanoid
Chimp
phosphoglucomutase 2 like 1
Macaque
phosphoglucomutase 2 like 1
Mouse
Rat
Dog
phosphoglucomutase 2 like 1
Publication Statistics
PubMed Score 5.06
PubMed score by year
PubTator Score 4.59
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title