Protein Summary
Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane (By similarity). This gene encodes a transmembrane glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Jan 2009]
- ENST00000303221
- ENSP00000302289
- ENSG00000170571
- ENST00000514111
- ENSP00000426404
- GP70
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 0.96 | ||
virus perturbation | 0.94 | ||
kinase | 0.85 | ||
PubMedID | 0.82 | ||
protein domain | 0.73 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 773.25 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 184 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 773.25 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 184 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (42)
SLC16A11
Family: Transporter
Novelty: 0.07860306
p_int: 0.999994912
p_ni: 0.000005087
p_wrong: 1e-9
Score: 0.398
Data Source: BioPlex,STRINGDB
IL20
Novelty: 0.78184288
p_int: 0.999459694
p_ni: 0.000536659
p_wrong: 0.000003646
Data Source: BioPlex
LGALS3
Novelty: 0.00032754
p_int: 0.99795564
p_ni: 0.002041252
p_wrong: 0.000003107
Score: 0.171
Data Source: BioPlex,STRINGDB
FNDC11
Novelty: 20.00979352
p_int: 0.997547356
p_ni: 0.002450325
p_wrong: 0.000002319
Score: 0.228
Data Source: BioPlex,STRINGDB
LPCAT2
Family: Enzyme
Novelty: 0.02794035
p_int: 0.997380445
p_ni: 0.002512242
p_wrong: 0.000107313
Data Source: BioPlex
HSD17B1
Family: Enzyme
Novelty: 0.00313425
p_int: 0.997334253
p_ni: 0.002489045
p_wrong: 0.000176702
Data Source: BioPlex
DHRS9
Family: Enzyme
Novelty: 0.00256743
p_int: 0.997145736
p_ni: 0.002849958
p_wrong: 0.000004306
Score: 0.163
Data Source: BioPlex,STRINGDB
OS9
Novelty: 0.01490339
p_int: 0.996756746
p_ni: 0.003142908
p_wrong: 0.000100347
Score: 0.152
Data Source: BioPlex,STRINGDB
RCL1
Family: Enzyme
Novelty: 0.02116964
p_int: 0.996172835
p_ni: 0.000876021
p_wrong: 0.002951144
Data Source: BioPlex
LGALS8
Novelty: 0.00623836
p_int: 0.995872191
p_ni: 0.004110958
p_wrong: 0.000016851
Data Source: BioPlex
Nearest Tclin Targets
Pathways (4)
Reactome (4)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Proton-coupled monocarboxylate transport | ||||
Reactome | SLC-mediated transmembrane transport | ||||
Reactome | Transport of bile salts and organic acids, metal ions and amine compounds | ||||
Reactome | Transport of small molecules | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Proton-coupled monocarboxylate transport | ||||
SLC-mediated transmembrane transport | ||||
Transport of bile salts and organic acids, metal ions and amine compounds | ||||
Transport of small molecules | ||||
Viral Interactions (0)
Gene Ontology Terms (11)
Functions (2)
Components (5)
Processes (4)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | Reactome | |||
Disease Associations ()
GWAS Traits (1)
Items per page:
1 – 1 of 1
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
1 | 1 | 0 | 1.1 | 1.1 | |||||
Items per page:
1 – 1 of 1
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.1 | 1.1 | |||||
Find similar targets by:
IDG Resources
Orthologs (13)
1 – 5 of 13
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | embigin | VGNC:3977 | 461886 | |||||
Macaque | embigin | 702068 | ||||||
Mouse | MGI:95321 | 13723 | ||||||
Rat | RGD:621067 | 114511 | ||||||
Dog | embigin | VGNC:50876 | 479340 | |||||
Publication Statistics
PubMed Score 773.25
PubMed score by year
PubTator Score 299.07
PubTator score by year
Related Publications
Text Mined References (9)
GeneRif Annotations (4)
Items per page:
0 of 0
PMID | Year | Title |
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