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Tdark
ZNF449
Zinc finger protein 449

Protein Summary
Description
May be involved in transcriptional regulation. This gene encodes a nuclear protein that likely functions as a transcription factor. The protein includes an N-terminal SCAN domain, and seven C2H2-type zinc finger motifs. [provided by RefSeq, May 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000339249
  • ENSP00000339585
  • ENSG00000173275
  • ENST00000370761
  • ENSP00000359797

Symbol
  • ZSCAN19
  • ZSCAN19
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.73
microRNA
0.66
transcription factor
0.58
tissue sample
0.51
tissue
0.48


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.58   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 152   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.58   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 152   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 449
VGNC:1179
473793
Macaque
zinc finger protein 449
711148
Mouse
MGI:1925869
78619
Rat
RGD:1584453
684901
Dog
zinc finger protein 449
VGNC:48731
492160
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 449
Macaque
zinc finger protein 449
Mouse
Rat
Dog
zinc finger protein 449
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6P9G9-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (12)
1 – 10 of 12
ZSCAN20
Tdark
Family: TF
Novelty: 0.37441538
p_int: 0.99671601
p_ni: 0.000001017
p_wrong: 0.003282973
Score: 0.232
Data Source: BioPlex,STRINGDB
KRBOX4
Tdark
Novelty: 0.6803597
Score: 0.585
Data Source: STRINGDB
SEC14L5
Tdark
Novelty: 0.32185533
Score: 0.526
Data Source: STRINGDB
ZNF608
Tdark
Novelty: 0.18575706
Score: 0.522
Data Source: STRINGDB
PRRC2B
Tdark
Novelty: 0.28608235
Score: 0.484
Data Source: STRINGDB
IRF2BPL
Tdark
Novelty: 0.05458595
Score: 0.469
Data Source: STRINGDB
GTF2IRD2
Tbio
Family: TF
Novelty: 0.16720387
Score: 0.465
Data Source: STRINGDB
WIPF3
Tdark
Novelty: 0.0257625
Score: 0.454
Data Source: STRINGDB
COL2A1
Tbio
Novelty: 0.0011102
Score: 0.451
Data Source: STRINGDB
GTF2IRD2B
Tbio
Family: TF
Novelty: 0.14868633
Score: 0.433
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.58

PubMed score by year
PubTator Score  1.2

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer