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Tbio
CCDC62
Coiled-coil domain-containing protein 62

Protein Summary
Description
Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000253079
  • ENSP00000253079
  • ENSG00000130783
  • ENST00000341952
  • ENSP00000341471
  • ENST00000392441
  • ENSP00000376236
  • ENST00000537566
  • ENSP00000445045

Symbol
  • CT109
  • ERAP75
  • TSP-NY
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.84
cell type or tissue
0.69
tissue sample
0.6
cellular component
0.54
cell line
0.52


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.56   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 63   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.56   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0