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Tdark
ZNF549
Zinc finger protein 549

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000240719
  • ENSP00000240719
  • ENSG00000121406
  • ENST00000376233
  • ENSP00000365407
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.73
microRNA
0.72
protein domain
0.58
tissue
0.55
tissue sample
0.45


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.14   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 52   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.14   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 52   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
balding measurement
1
1
1
42.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
balding measurement
1
42.3
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 549
VGNC:2150
456329
Macaque
zinc finger protein 549
708201
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 549
Macaque
zinc finger protein 549
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6P9A3-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (14)
1 – 10 of 14
SORL1
Tbio
Novelty: 0.00380895
p_int: 0.784874581
p_ni: 0.215125419
Score: 0.19
Data Source: BioPlex,STRINGDB
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.92
Data Source: STRINGDB
WFDC10B
Tdark
Novelty: 0.9331351
Score: 0.556
Data Source: STRINGDB
R3HCC1
Tdark
Novelty: 1.93729169
Score: 0.531
Data Source: STRINGDB
KIAA1211L
Tdark
Novelty: 1.5913836
Score: 0.53
Data Source: STRINGDB
TIMM29
Tdark
Novelty: 0.51321672
Score: 0.511
Data Source: STRINGDB
CCDC85C
Tdark
Novelty: 0.30053883
Score: 0.474
Data Source: STRINGDB
C11orf21
Tdark
Novelty: 0.45801604
Score: 0.473
Data Source: STRINGDB
LMAN1L
Tbio
Novelty: 0.24759008
Score: 0.473
Data Source: STRINGDB
ATXN7L1
Tdark
Novelty: 0.43694835
Score: 0.466
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.14

PubMed score by year
PubTator Score  0.14

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer