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Tbio
GALNT18
Polypeptide N-acetylgalactosaminyltransferase 18

Protein Summary
Description
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000227756
  • ENSP00000227756
  • ENSG00000110328

Symbol
  • GALNTL4
  • GALNT15
  • GALNTL4
  • GALNACT18
  • GalNAc-T15
  • GalNAc-T18
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.86
transcription factor binding site profile
0.8
kinase perturbation
0.76
cell type or tissue
0.68
disease
0.66


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.29   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 47   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.29   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 47   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0