NOTUM
Palmitoleoyl-protein carboxylesterase NOTUM
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.78 | ||
kinase perturbation | 0.76 | ||
transcription factor binding site profile | 0.74 | ||
PubMedID | 0.6 | ||
transcription factor | 0.59 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Hedgehog ligand biogenesis | ||||
Reactome | Metabolism of proteins | ||||
Reactome | Post-translational protein modification | ||||
Reactome | Post-translational protein phosphorylation | ||||
Reactome | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Hedgehog ligand biogenesis | ||||
Metabolism of proteins | ||||
Post-translational protein modification | ||||
Post-translational protein phosphorylation | ||||
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 2 | 5 | 6 | 76.5 | |||||
vital capacity | 1 | 1 | 1 | 73.2 | |||||
BMI-adjusted waist-hip ratio | 2 | 3 | 3 | 58.3 | |||||
birth weight | 2 | 2 | 2 | 55.2 | |||||
forced expiratory volume | 1 | 1 | 1 | 46.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 6 | 76.5 | |||||
vital capacity | 1 | 73.2 | |||||
BMI-adjusted waist-hip ratio | 3 | 58.3 | |||||
birth weight | 2 | 55.2 | |||||
forced expiratory volume | 1 | 46.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | notum, palmitoleoyl-protein carboxylesterase | VGNC:9485 | 100609059 | |||||
Mouse | MGI:1924833 | 77583 | ||||||
Rat | RGD:1307119 | 303743 | ||||||
Dog | notum, palmitoleoyl-protein carboxylesterase | VGNC:43901 | 483374 | |||||
Horse | notum, palmitoleoyl-protein carboxylesterase | VGNC:20820 | 100054869 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | notum, palmitoleoyl-protein carboxylesterase | |||||
Mouse | ||||||
Rat | ||||||
Dog | notum, palmitoleoyl-protein carboxylesterase | |||||
Horse | notum, palmitoleoyl-protein carboxylesterase | |||||
PMID | Year | Title |
---|