Tbio FDX2 Ferredoxin-2, mitochondrial

Protein Summary

Description

Essential for heme A and Fe/S protein biosynthesis. This gene encodes a member of the ferredoxin family. The encoded protein contains a 2Fe-2S ferredoxin-type domain and is essential for heme A and Fe/S protein biosynthesis. Mutation in FDX1L gene is associated with mitochondrial muscle myopathy. [provided by RefSeq, Sep 2014]

Uniprot Accession IDs

• Q6P4F2
• B7Z6L7
• Q8N8B8

Gene Name

• FDX2

Ensembl ID

• ENST00000393708
• ENSP00000377311
• ENSG00000267673

Symbol

• FDX1L
• FDX1L
• MEOAL

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0
biological term	0
cell line	0
cell type or tissue	0
cellular component	0

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.26   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 7   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.26   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 7   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0