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Tdark
FUT10
Alpha-(1,3)-fucosyltransferase 10

Protein Summary
Description
Probable fucosyltransferase.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000327671
  • ENSP00000332757
  • ENSG00000172728
  • ENST00000518672
  • ENSP00000430428
  • ENST00000524021
  • ENSP00000429870

Symbol
  • FUCTX
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.82
biological process
0.66
histone modification site profile
0.64
cellular component
0.56
virus perturbation
0.55


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.34   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 146   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.34   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 146   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 12
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
pulse pressure measurement
1
1
1
30.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
pulse pressure measurement
1
30.5
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
fucosyltransferase 10
VGNC:12014
747350
Macaque
fucosyltransferase 10
697659
Mouse
MGI:2384748
171167
Rat
RGD:1359164
497619
Dog
fucosyltransferase 10
VGNC:41012
503548
Species
Name
OMA
EggNOG
Inparanoid
Chimp
fucosyltransferase 10
Macaque
fucosyltransferase 10
Mouse
Rat
Dog
fucosyltransferase 10
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6P4F1-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (5)
Blood group systems biosynthesis (R-HSA-9033658)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Blood group systems biosynthesis
Reactome
Lewis blood group biosynthesis
Reactome
Metabolism
Reactome
Metabolism of carbohydrates
Name
Explore in Pharos
Explore in Source
Blood group systems biosynthesis
Lewis blood group biosynthesis
Metabolism
Metabolism of carbohydrates
Gene Ontology Terms (17)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (21)
1 – 10 of 21
PLTP
Tbio
Novelty: 0.00267612
p_int: 0.982655842
p_ni: 0.000058727
p_wrong: 0.017285431
Score: 0.214
Data Source: BioPlex,STRINGDB
TMED6
Tdark
Novelty: 0.598611
p_int: 0.930234389
p_ni: 0.000076806
p_wrong: 0.069688804
Score: 0.187
Data Source: BioPlex,STRINGDB
FUT8
Tbio
Family: Enzyme
Novelty: 0.00675388
Score: 0.724
Data Source: STRINGDB
POFUT2
Tbio
Family: Enzyme
Novelty: 0.06236603
Score: 0.688
Data Source: STRINGDB
POFUT1
Tbio
Family: Enzyme
Novelty: 0.0176011
Score: 0.65
Data Source: STRINGDB
B3GNT2
Tbio
Family: Enzyme
Novelty: 0.02724566
Score: 0.633
Data Source: STRINGDB
LPAR2
Tchem
Family: GPCR
Novelty: 0.00794134
Score: 0.62
Data Source: STRINGDB
FUT1
Tbio
Family: Enzyme
Novelty: 0.00597206
Score: 0.553
Data Source: STRINGDB
AKTIP
Tbio
Novelty: 0.00315951
Score: 0.522
Data Source: STRINGDB
FUT2
Tbio
Family: Enzyme
Novelty: 0.0009286
Score: 0.498
Data Source: STRINGDB
Publication Statistics
PubMed Score  3.34

PubMed score by year
PubTator Score  0.93

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer