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Tdark
XRRA1
X-ray radiation resistance-associated protein 1

Protein Summary
Description
May be involved in the response of cells to X-ray radiation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000321448
  • ENSP00000319303
  • ENSG00000166435
  • ENST00000340360
  • ENSP00000339918
  • ENST00000527087
  • ENSP00000435838
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.7
transcription factor binding site profile
0.64
histone modification site profile
0.61
tissue sample
0.6
microRNA
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.55   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 48   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.55   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 48   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (37)
1 – 10 of 37
HSPA8
Tchem
Novelty:  0.00081014
p_int:  0.89065098
p_ni:  0.10934902
Data Source:  BioPlex
KIAA0232
Tdark
Novelty:  2.37569744
p_int:  0.866188277
p_ni:  0.133671948
p_wrong:  0.000139775
Data Source:  BioPlex
AP5B1
Tdark
Novelty:  0.06116142
p_int:  0.783636768
p_ni:  0.011374259
p_wrong:  0.204988973
Data Source:  BioPlex
SPCS2
Tdark
Family:  Enzyme
Novelty:  0.21358992
Score:  0.774
Data Source:  STRINGDB
XRCC5
Tbio
Novelty:  0.00150735
Score:  0.756
Data Source:  STRINGDB
PPME1
Tchem
Family:  Enzyme
Novelty:  0.01559862
Score:  0.73
Data Source:  STRINGDB
POLD3
Tbio
Family:  Enzyme
Novelty:  0.02646621
Score:  0.722
Data Source:  STRINGDB
ADGRL1
Tbio
Family:  GPCR
Novelty:  0.00957739
Score:  0.685
Data Source:  STRINGDB
ADGRL2
Tbio
Family:  GPCR
Novelty:  0.00985539
Score:  0.685
Data Source:  STRINGDB
ADGRL3
Tbio
Family:  GPCR
Novelty:  0.00268343
Score:  0.685
Data Source:  STRINGDB
Gene Ontology Terms (5)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
UniProtKB
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.2
70.5
1
1
0
1.2
70.5
electrocardiography
1
1
8
45.2
1
1
1
15.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.2
70.5
0
1.2
70.5
electrocardiography
8
45.2
1
15.8
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
X-ray radiation resistance associated 1
VGNC:938
466708
Macaque
X-ray radiation resistance associated 1
693788
Mouse
MGI:2181647
446101
Dog
X-ray radiation resistance associated 1
VGNC:48473
476805
Horse
X-ray radiation resistance associated 1
VGNC:25087
100064954
Species
Name
OMA
EggNOG
Inparanoid
Chimp
X-ray radiation resistance associated 1
Macaque
X-ray radiation resistance associated 1
Mouse
Dog
X-ray radiation resistance associated 1
Horse
X-ray radiation resistance associated 1
Publication Statistics
PubMed Score 2.55
PubMed score by year
PubTator Score 1.83
PubTator score by year