MED27
Mediator of RNA polymerase II transcription subunit 27
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.91 | ||
phenotype | 0.82 | ||
interacting protein | 0.81 | ||
gene perturbation | 0.76 | ||
transcription factor binding site profile | 0.74 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Developmental Biology | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Developmental Biology | ||||
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
Metabolism | ||||
Metabolism of lipids | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
self reported educational attainment | 4 | 5 | 5 | 5.6 | 91.8 | ||||
cognitive function measurement | 3 | 3 | 4 | 80 | |||||
mathematical ability | 3 | 2 | 4 | 74 | |||||
smoking status measurement | 2 | 1 | 2 | 50.6 | |||||
insomnia measurement | 1 | 2 | 0 | 1 | 43.9 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
self reported educational attainment | 5 | 5.6 | 91.8 | ||||
cognitive function measurement | 4 | 80 | |||||
mathematical ability | 4 | 74 | |||||
smoking status measurement | 2 | 50.6 | |||||
insomnia measurement | 0 | 1 | 43.9 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | mediator complex subunit 27 | 715219 | ||||||
Mouse | MGI:1916225 | 68975 | ||||||
Rat | RGD:1564993 | 296612 | ||||||
Dog | mediator complex subunit 27 | VGNC:43134 | 612800 | |||||
Horse | mediator complex subunit 27 | VGNC:20084 | 100069513 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | mediator complex subunit 27 | |||||
Mouse | ||||||
Rat | ||||||
Dog | mediator complex subunit 27 | |||||
Horse | mediator complex subunit 27 | |||||
PMID | Year | Title |
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