Protein Summary
ATPase which is preferentially stimulated by single-stranded DNA and is involved in homologous recombination repair (HRR). Has a DNA-binding activity which is independent of its ATPase activity.
- ENST00000312423
- ENSP00000310008
- ENSG00000173928
- C19orf39
- SWS1AP1
- C19orf39
- ZSWIM7AP1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.67 | ||
molecular function | 0.56 | ||
transcription factor binding site profile | 0.55 | ||
cell line | 0.51 | ||
tissue | 0.49 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.46 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 54 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.46 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 54 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0