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Tdark
ZNF280D
Zinc finger protein 280D

Protein Summary
Description
May function as a transcription factor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000267807
  • ENSP00000267807
  • ENSG00000137871
  • ENST00000558067
  • ENSP00000454173
  • ENST00000558320
  • ENSP00000453706
  • ENST00000559237
  • ENSP00000454111
  • ENST00000560002
  • ENSP00000453636

Symbol
  • KIAA1584
  • SUHW4
  • ZNF634
  • SUHW4
  • ZNF634
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.68
cell type or tissue
0.62
microRNA
0.61
transcription factor binding site profile
0.61
cell line
0.6


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.46   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 57   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.46   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 57   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (41)
MCRIP2
Tdark
Novelty:  1.50465727
Score:  0.712
Data Source:  STRINGDB
FAM227B
Tdark
Novelty:  9
Score:  0.679
Data Source:  STRINGDB
WDR70
Tdark
Novelty:  0.37521871
Score:  0.639
Data Source:  STRINGDB
SMC5
Tbio
Novelty:  0.008623
Score:  0.586
Data Source:  STRINGDB
FAM214A
Tdark
Novelty:  0.60540836
Score:  0.585
Data Source:  STRINGDB
TSGA10IP
Tdark
Novelty:  20.75428866
Score:  0.584
Data Source:  STRINGDB
OR8G1
Tdark
Family:  oGPCR
Novelty:  9.20634921
Score:  0.582
Data Source:  STRINGDB
NPIPB8
Tdark
Novelty:  2.67367838
Score:  0.543
Data Source:  STRINGDB
PAIP2B
Tbio
Novelty:  0.65592664
Score:  0.527
Data Source:  STRINGDB
NOP9
Tdark
Novelty:  2.89535198
Score:  0.526
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (6)
Find Similar Targets
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations ()
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
2
2
1
1.1
49.4
grip strength measurement
1
1
1
48.5
biological sex
1
1
1
10.6
platelet count
1
1
1
10.5
intraocular pressure measurement
2
1
2
7.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
1.1
49.4
grip strength measurement
1
48.5
biological sex
1
10.6
platelet count
1
10.5
intraocular pressure measurement
2
7.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 280D
453464
Macaque
zinc finger protein 280D
699509
Mouse
MGI:2384583
235469
Rat
RGD:1560796
315798
Dog
zinc finger protein 280D
VGNC:49825
478315
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 280D
Macaque
zinc finger protein 280D
Mouse
Rat
Dog
zinc finger protein 280D
Publication Statistics
PubMed Score 0.46
PubMed score by year
PubTator Score 0.42
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title