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Tdark
ZNF770
Zinc finger protein 770

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000356321
  • ENSP00000348673
  • ENSG00000198146

Symbol
  • PRO1914
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.72
histone modification site profile
0.71
small molecule perturbation
0.64
transcription factor binding site profile
0.63
transcription factor perturbation
0.61


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.23   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 17   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.23   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 17   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
2
1
2
46.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
2
46.4
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 770
VGNC:13464
735642
Mouse
MGI:2445100
228491
Rat
RGD:1597283
691610
Dog
zinc finger protein 770
VGNC:48812
100687020
Horse
zinc finger protein 770
VGNC:25385
100071735
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 770
Mouse
Rat
Dog
zinc finger protein 770
Horse
zinc finger protein 770
Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (36)
1 – 10 of 36
ZNF2
Tbio
Family: TF
Novelty: 0.01062543
p_int: 0.978378577
p_ni: 0.021621419
p_wrong: 4e-9
Data Source: BioPlex
PPAN
Tbio
Novelty: 0.01063709
p_int: 0.915005067
p_ni: 0.08434221
p_wrong: 0.000652723
Data Source: BioPlex
RPL11
Tbio
Novelty: 0.00448962
p_int: 0.896969501
p_ni: 0.103030494
p_wrong: 5e-9
Data Source: BioPlex
CACNG5
Tdark
Family: IC
Novelty: 0.52705448
p_int: 0.883316378
p_ni: 0.116675548
p_wrong: 0.000008074
Data Source: BioPlex
FGF17
Tbio
Novelty: 0.01432991
p_int: 0.87067669
p_ni: 0.129323032
p_wrong: 2.78e-7
Data Source: BioPlex
RPL7A
Tbio
Novelty: 0.01674027
p_int: 0.86232384
p_ni: 0.137675882
p_wrong: 2.78e-7
Data Source: BioPlex
WDR46
Tbio
Novelty: 0.19307408
p_int: 0.828057812
p_ni: 0.171941917
p_wrong: 2.71e-7
Data Source: BioPlex
NIFK
Tbio
Novelty: 0.01221562
p_int: 0.824518675
p_ni: 0.175284953
p_wrong: 0.000196372
Score: 0.232
Data Source: BioPlex,STRINGDB
E4F1
Tbio
Family: TF
Novelty: 0.02192338
p_int: 0.818938418
p_ni: 0.181061553
p_wrong: 2.9e-8
Data Source: BioPlex
H2AFY2
Tbio
Novelty: 0.09948698
p_int: 0.762660208
p_ni: 0.237339781
p_wrong: 1.1e-8
Score: 0.159
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  1.23

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer