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Tdark
DHRS7B
Dehydrogenase/reductase SDR family member 7B

Protein Summary
Description
Putative oxidoreductase. This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000395511
  • ENSP00000378887
  • ENSG00000109016

Symbol
  • SDR32C1
  • CGI-93
  • SDR32C1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.96
histone modification site profile
0.86
transcription factor perturbation
0.84
transcription factor binding site profile
0.8
transcription factor
0.72


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.51   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 129   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.51   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 129   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
1
1
41.8
fasting blood glucose measurement
1
1
1
30.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
41.8
fasting blood glucose measurement
1
30.8
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
dehydrogenase/reductase 7B
VGNC:12091
454512
Macaque
dehydrogenase/reductase 7B
704869
Mouse
MGI:2384931
216820
Rat
RGD:1311243
287380
Dog
dehydrogenase/reductase 7B
VGNC:54295
479531
Species
Name
OMA
EggNOG
Inparanoid
Chimp
dehydrogenase/reductase 7B
Macaque
dehydrogenase/reductase 7B
Mouse
Rat
Dog
dehydrogenase/reductase 7B
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6IAN0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Metabolism (R-HSA-1430728)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism
Reactome
Metabolism of lipids
Reactome
Plasmalogen biosynthesis
Reactome
Wax and plasmalogen biosynthesis
Name
Explore in Pharos
Explore in Source
Metabolism
Metabolism of lipids
Plasmalogen biosynthesis
Wax and plasmalogen biosynthesis
Gene Ontology Terms (7)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (24)
1 – 10 of 24
GYPB
Tbio
Novelty: 0.00442195
p_int: 0.758216893
p_ni: 0.241783107
Score: 0.225
Data Source: BioPlex,STRINGDB
RAB7A
Tbio
Family: Enzyme
Novelty: 0.00192702
Score: 0.87
Data Source: STRINGDB
RAB1B
Tbio
Family: Enzyme
Novelty: 0.02156819
Score: 0.828
Data Source: STRINGDB
TMEM11
Tbio
Novelty: 0.00067837
Score: 0.64
Data Source: STRINGDB
NATD1
Tdark
Novelty: 8.93728223
Score: 0.604
Data Source: STRINGDB
PRR7
Tbio
Novelty: 0.08132975
Score: 0.594
Data Source: STRINGDB
SPATA2L
Tdark
Novelty: 1.32317574
Score: 0.539
Data Source: STRINGDB
GPATCH2L
Tdark
Novelty: 1.68490464
Score: 0.538
Data Source: STRINGDB
DNAJC8
Tbio
Novelty: 0.27669763
Score: 0.536
Data Source: STRINGDB
DRC3
Tdark
Novelty: 0.99283468
Score: 0.503
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.51

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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