Tdark ABLIM2 Actin-binding LIM protein 2

Protein Summary

Description

May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity.

Uniprot Accession IDs

• Q6H8Q1
• E9PF39
• Q08E71
• Q19VH0
• Q6H8Q0
• Q6NX73
• Q8N3C5
• Q8N9E9
• Q8N9G2
• Q96JL7
• abLIM-2

Gene Name

• ABLIM2

Ensembl ID

• ENST00000341937
• ENSP00000342813
• ENSG00000163995
• ENST00000361581
• ENSP00000355003
• ENST00000361737
• ENSP00000354887
• ENST00000407564
• ENSP00000384658
• ENST00000428004
• ENSP00000389410
• ENST00000447017
• ENSP00000393511
• ENST00000505872
• ENSP00000421283
• ENST00000514025
• ENSP00000423661

Symbol

• KIAA1808

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.83
microRNA	0.68
transcription factor binding site profile	0.66
PubMedID	0.64
biological process	0.59

Protein Classes

PANTHER Classes

Protein / Structural Protein / Actin-binding Lim Protein 2

Protein / Cytoskeletal Protein / Actin Family Cytoskeletal Protein / Actin-binding Lim Protein 2

DTO Classes

Protein / Cellular Structure / Actin Family Cytoskeletal Protein / Actin-binding Lim Protein 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.59   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 41   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.59   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 41   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0