You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
PTRHD1
Putative peptidyl-tRNA hydrolase PTRHD1

Protein Summary
Description
This gene encodes the enzyme peptidyl-tRNA hydrolase. Peptidyl-tRNA hydrolases perform the essential function of recycling peptidyl-tRNAs. Mutations in this gene are associated with autosomal-recessive intellectual disability and parkinsonism. [provided by RefSeq, May 2017]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000328379
  • ENSP00000330389
  • ENSG00000184924

Symbol
  • C2orf79
  • C2orf79
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.92
virus perturbation
0.85
transcription factor perturbation
0.74
cell type or tissue
0.67
kinase perturbation
0.6


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.09   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 14   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.09   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 14   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
peptidyl-tRNA hydrolase domain containing 1
VGNC:352
738617
Macaque
peptidyl-tRNA hydrolase domain containing 1
693395
Mouse
MGI:1916959
69709
Rat
RGD:1561792
298861
Dog
peptidyl-tRNA hydrolase domain containing 1
VGNC:49888
475685
Species
Name
OMA
EggNOG
Inparanoid
Chimp
peptidyl-tRNA hydrolase domain containing 1
Macaque
peptidyl-tRNA hydrolase domain containing 1
Mouse
Rat
Dog
peptidyl-tRNA hydrolase domain containing 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6GMV3-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-EC
Protein-Protein Interactions (23)
1 – 10 of 23
C6orf89
Tbio
Novelty: 0.30232231
p_int: 0.967257632
p_ni: 0.027077044
p_wrong: 0.005665323
Score: 0.685
Data Source: BioPlex,STRINGDB
P2RY12
Tclin
Family: GPCR
Novelty: 0.00035406
p_int: 0.750266971
p_ni: 0.002442937
p_wrong: 0.247290091
Score: 0.189
Data Source: BioPlex,STRINGDB
C6orf120
Tdark
Novelty: 0.90888293
Score: 0.67
Data Source: STRINGDB
METTL15
Tdark
Family: Enzyme
Novelty: 0.4575663
Score: 0.649
Data Source: STRINGDB
WDR27
Tdark
Novelty: 1.32523881
Score: 0.641
Data Source: STRINGDB
DCAF16
Tdark
Novelty: 0.35666992
Score: 0.609
Data Source: STRINGDB
CENPO
Tbio
Novelty: 0.12059767
Score: 0.593
Data Source: STRINGDB
TCTE3
Tdark
Novelty: 0.15747856
Score: 0.577
Data Source: STRINGDB
EFR3B
Tbio
Novelty: 0.61495463
Score: 0.567
Data Source: STRINGDB
PSMB1
Tclin
Family: Enzyme
Novelty: 0.0255917
Score: 0.548
Data Source: STRINGDB
Publication Statistics
PubMed Score  4.09

PubMed score by year
PubTator Score  3.97

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer