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Tbio
SMYD5
SET and MYND domain-containing protein 5

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000389501
  • ENSP00000374152
  • ENSG00000135632

Symbol
  • RAI15
  • RRG1
  • RAI15
  • NN8-4AG
  • ZMYND23
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.95
histone modification site profile
0.88
transcription factor binding site profile
0.72
cell line
0.62
small molecule perturbation
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.71   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 208   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.71   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 208   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (35)
1 – 10 of 35
SMYD4
Tbio
Family:  Epigenetic
Novelty:  0.18455037
Score:  0.9
Data Source:  STRINGDB
SMYD1
Tbio
Family:  Epigenetic
Novelty:  0.03781475
Score:  0.692
Data Source:  STRINGDB
GPRC5A
Tbio
Family:  GPCR
Novelty:  0.02060511
Score:  0.673
Data Source:  STRINGDB
HGH1
Tdark
Novelty:  10.01230391
Score:  0.601
Data Source:  STRINGDB
NUS1
Tbio
Family:  Enzyme
Novelty:  0.02022029
Score:  0.567
Data Source:  STRINGDB
KMT5B
Tchem
Family:  Epigenetic
Novelty:  0.04892469
Score:  0.553
Data Source:  STRINGDB
MTMR14
Tbio
Family:  Enzyme
Novelty:  0.07074944
Score:  0.54
Data Source:  STRINGDB
KDM7A
Tchem
Family:  Epigenetic
Novelty:  0.04113733
Score:  0.519
Data Source:  STRINGDB
FBXL19
Tbio
Novelty:  0.07526966
Score:  0.517
Data Source:  STRINGDB
SLC39A13
Tbio
Family:  Transporter
Novelty:  0.03474449
Score:  0.506
Data Source:  STRINGDB
Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urinary metabolite measurement
1
2
3
81.4
intelligence
2
5
3
6.2
65.5
glomerular filtration rate
1
1
1
47.7
self reported educational attainment
2
2
2
46.9
bone density
1
1
2
29
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urinary metabolite measurement
3
81.4
intelligence
3
6.2
65.5
glomerular filtration rate
1
47.7
self reported educational attainment
2
46.9
bone density
2
29
Find similar targets by:
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SMYD family member 5
VGNC:379
459322
Macaque
SMYD family member 5
705926
Mouse
MGI:108048
232187
Rat
RGD:1309153
312503
Dog
SMYD family member 5
VGNC:46583
475798
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SMYD family member 5
Macaque
SMYD family member 5
Mouse
Rat
Dog
SMYD family member 5
Publication Statistics
PubMed Score 10.71
PubMed score by year
PubTator Score 2.50
PubTator score by year