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Tbio
ADAL
Adenosine deaminase-like protein

Protein Summary
Description
Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000389651
  • ENSP00000374302
  • ENSG00000168803
  • ENST00000422466
  • ENSP00000398744
  • ENST00000428046
  • ENSP00000413074
  • ENST00000562188
  • ENSP00000456242
  • ENST00000610420
  • ENSP00000478575
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.72
biological process
0.62
histone modification site profile
0.62
transcription factor
0.61
microRNA
0.6


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.35   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 83   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.35   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 83   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (119)
ADARB2
Tbio
Family:  Enzyme
Novelty:  0.01387325
Score:  0.886
Data Source:  STRINGDB
ADARB1
Tbio
Family:  Enzyme
Novelty:  0.00586819
Score:  0.881
Data Source:  STRINGDB
NXPE3
Tdark
Novelty:  1.5063521
Score:  0.827
Data Source:  STRINGDB
ENTPD3
Tchem
Family:  Enzyme
Novelty:  0.01673548
Score:  0.787
Data Source:  STRINGDB
RPP38
Tbio
Family:  Enzyme
Novelty:  0.06387902
Score:  0.785
Data Source:  STRINGDB
CNTD2
Tbio
Novelty:  0.25084152
Score:  0.763
Data Source:  STRINGDB
FOXR2
Tbio
Family:  TF
Novelty:  0.06548862
Score:  0.754
Data Source:  STRINGDB
TBC1D8B
Tdark
Novelty:  0.35419125
Score:  0.746
Data Source:  STRINGDB
GMPS
Tbio
Family:  Enzyme
Novelty:  0.00611806
Score:  0.73
Data Source:  STRINGDB
ADA2
Tbio
Family:  Enzyme
Novelty:  0.01077582
Score:  0.719
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (6)
Abacavir metabolism (R-HSA-2161541)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 6
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Abacavir metabolism
Reactome
Abacavir transport and metabolism
Reactome
Metabolism
Reactome
Metabolism of nucleotides
Reactome
Nucleotide salvage
Name
Explore in Pharos
Explore in Source
Abacavir metabolism
Abacavir transport and metabolism
Metabolism
Metabolism of nucleotides
Nucleotide salvage
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (35)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
22
2
25
96.6
high density lipoprotein cholesterol measurement
22
2
25
93.6
glycine measurement
2
2
2
87.5
liver volume
1
1
1
85.6
very low density lipoprotein cholesterol measurement
32
2
32
83.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
25
96.6
high density lipoprotein cholesterol measurement
25
93.6
glycine measurement
2
87.5
liver volume
1
85.6
very low density lipoprotein cholesterol measurement
32
83.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
adenosine deaminase like
VGNC:11786
453376
Macaque
adenosine deaminase like
710148
Mouse
MGI:1923144
75894
Dog
adenosine deaminase like
VGNC:37572
100856728
Horse
adenosine deaminase like
VGNC:15044
100070813
Species
Name
OMA
EggNOG
Inparanoid
Chimp
adenosine deaminase like
Macaque
adenosine deaminase like
Mouse
Dog
adenosine deaminase like
Horse
adenosine deaminase like
Publication Statistics
PubMed Score 14.35
PubMed score by year
PubTator Score 5.81
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title