You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
ZNF660
Zinc finger protein 660

Protein Summary
Description
May be involved in transcriptional regulation. This gene encodes a protein that contains multiple C2H2 zinc finger domains, and is located in a cluster of zinc-finger encoding genes on chromosome 3. Naturally-occurring readthrough transcription is observed between this gene and the downstream zinc finger protein 197 gene and is represented by GeneID:110354863. [provided by RefSeq, May 2017]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000322734
  • ENSP00000324605
  • ENSG00000144792
  • ENST00000625494
  • ENSP00000487319
  • ENSG00000280661
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.67
tissue sample
0.52
cell line
0.47
tissue
0.44
kinase perturbation
0.42


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.48   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 119   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.48   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
Items per page:
1 – 2 of 2
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
macrophage inflammatory protein 1b measurement
1
1
1
34
macrophage inflammatory protein 1b measurement
1
1
1
34
Items per page:
1 – 2 of 2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
macrophage inflammatory protein 1b measurement
1
34
macrophage inflammatory protein 1b measurement
1
34
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 660
106996939
Species
Name
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 660
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6AZW8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (11)
1 – 10 of 11
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.903
Data Source: STRINGDB
CCDC181
Tdark
Novelty: 0.52897379
Score: 0.559
Data Source: STRINGDB
SCUBE3
Tbio
Novelty: 0.08124826
Score: 0.46
Data Source: STRINGDB
CREB3L3
Tbio
Family: TF
Novelty: 0.02519904
Score: 0.46
Data Source: STRINGDB
KIN
Tbio
Novelty: 0.01425955
Score: 0.448
Data Source: STRINGDB
HEXIM1
Tbio
Novelty: 0.0142443
Score: 0.444
Data Source: STRINGDB
TEX45
Tdark
Novelty: 5.55785981
Score: 0.443
Data Source: STRINGDB
HAPLN3
Tdark
Novelty: 0.19545048
Score: 0.441
Data Source: STRINGDB
ZFR
Tbio
Novelty: 0.01859772
Score: 0.429
Data Source: STRINGDB
LAGE3
Tdark
Novelty: 0.02099961
Score: 0.418
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.48

PubMed score by year
PubTator Score  0.25

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer