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Tbio
HEATR6
HEAT repeat-containing protein 6

Protein Summary
Description
Amplification-dependent oncogene.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000184956
  • ENSP00000184956
  • ENSG00000068097

Symbol
  • ABC1
  • ABC1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.86
cell line
0.68
transcription factor binding site profile
0.68
transcription factor perturbation
0.61
disease perturbation
0.56


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.36   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 55   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.36   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 55   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
HEAT repeat containing 6
VGNC:9317
468427
Macaque
HEAT repeat containing 6
720089
Mouse
MGI:1919790
217026
Rat
RGD:1566204
497972
Dog
HEAT repeat containing 6
VGNC:41638
480598
Species
Name
OMA
EggNOG
Inparanoid
Chimp
HEAT repeat containing 6
Macaque
HEAT repeat containing 6
Mouse
Rat
Dog
HEAT repeat containing 6
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6AI08-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (112)
1 – 10 of 112
SDC2
Tbio
Novelty: 0.00597758
p_int: 0.980834337
p_ni: 0.019165663
Data Source: BioPlex
FIS1
Tbio
Novelty: 0.0033607
p_int: 0.9701176
p_ni: 0.0298824
Data Source: BioPlex
SNX21
Tdark
Novelty: 0.32916633
p_int: 0.951326079
p_ni: 0.048673921
Score: 0.172
Data Source: BioPlex,STRINGDB
GLMP
Tdark
Novelty: 0.10163099
p_int: 0.926942286
p_ni: 0.073057714
Data Source: BioPlex
CST8
Tbio
Novelty: 0.02316886
p_int: 0.901846022
p_ni: 0.098153978
Data Source: BioPlex
CD79B
Tclin
Novelty: 0.00227414
p_int: 0.894953389
p_ni: 0.105046611
Data Source: BioPlex
IQCF1
Tdark
Novelty: 0.78525464
p_int: 0.864102342
p_ni: 0.135897658
Data Source: BioPlex
BSG
Tbio
Novelty: 0.0010285
p_int: 0.857784145
p_ni: 0.142215855
Score: 0.157
Data Source: BioPlex,STRINGDB
OSTM1
Tbio
Novelty: 0.03033192
p_int: 0.82998524
p_ni: 0.17001476
Data Source: BioPlex
SPACA1
Tbio
Novelty: 0.07415851
p_int: 0.819104618
p_ni: 0.180895382
Data Source: BioPlex
Publication Statistics
PubMed Score  12.36

PubMed score by year
PubTator Score  28.66

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer