Tbio CWF19L1 CWF19-like protein 1

Protein Summary

Description

This gene encodes a member of the CWF19 protein family. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia-17 and mild cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Uniprot Accession IDs

• Q69YN2
• B4DHX1
• D3DR66
• Q5W0I3
• Q96HC3
• Q9H865
• Q9NV13
• C19L1

Gene Name

• CWF19L1

Ensembl ID

• ENST00000354105
• ENSP00000326411
• ENSG00000095485

Symbol

• C19L1
• hDrn1
• SCAR17

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.88
interacting protein	0.71
small molecule perturbation	0.69
tissue sample	0.64
transcription factor perturbation	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.84   (req: < 5)

Gene RIFs: 10   (req: <= 3)

Antibodies: 96   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.84   (req: >= 5)

Gene RIFs: 10   (req: > 3)

Antibodies: 96   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0