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Tbio
FMN1
Formin-1

Protein Summary
Description
Plays a role in the formation of adherens junction and the polymerization of linear actin cables. This gene belongs to the formin homology family and encodes a protein that has a role in the formation of adherens junction and the polymerization of linear actin cables. The homologous gene in mouse is associated with limb deformity. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000320930
  • ENSP00000325166
  • ENSG00000248905
  • ENST00000334528
  • ENSP00000333950
  • ENST00000558197
  • ENSP00000452984
  • ENST00000559047
  • ENSP00000454047
  • ENST00000616417
  • ENSP00000479134
  • ENST00000631469
  • ENSP00000488866
  • ENSG00000282513
  • ENST00000631756
  • ENSP00000488300
  • ENST00000631811
  • ENSP00000488198
  • ENST00000632024
  • ENSP00000488532
  • ENST00000633316
  • ENSP00000487643

Symbol
  • FMN
  • LD
  • LD
  • FMN
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.94
microRNA
0.87
trait
0.86
histone modification site profile
0.67
cell type or tissue
0.66


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 975.46   (req: < 5)
Gene RIFs: 11   (req: <= 3)
Antibodies: 92   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 975.46   (req: >= 5)
Gene RIFs: 11   (req: > 3)
Antibodies: 92   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 11
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0