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Tdark
MBLAC2
Metallo-beta-lactamase domain-containing protein 2

Protein Classes
Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000316610
  • ENSP00000314776
  • ENSG00000176055
  • ENST00000514906
  • ENSP00000425600
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.83
transcription factor binding site profile
0.71
microRNA
0.7
tissue sample
0.67
transcription factor perturbation
0.61


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.54   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 16   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.54   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 16   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
metallo-beta-lactamase domain containing 2
VGNC:6948
738321
Macaque
metallo-beta-lactamase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:33711]
Mouse
MGI:1920102
72852
Rat
RGD:1306703
365627
Dog
metallo-beta-lactamase domain containing 2
VGNC:43056
488914
Species
Name
OMA
EggNOG
Inparanoid
Chimp
metallo-beta-lactamase domain containing 2
Macaque
metallo-beta-lactamase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:33711]
Mouse
Rat
Dog
metallo-beta-lactamase domain containing 2
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q68D91-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (50)
1 – 10 of 50
CLCN7
Tchem
Family: IC
Novelty: 0.00764796
p_int: 0.999999154
p_ni: 8.46e-7
Score: 0.16
Data Source: BioPlex,STRINGDB
SLC9A6
Tbio
Family: Transporter
Novelty: 0.01410234
p_int: 0.999997184
p_ni: 0.000002816
Data Source: BioPlex
TMEM230
Tbio
Novelty: 0.04459055
p_int: 0.999996771
p_ni: 0.000003207
p_wrong: 2.2e-8
Score: 0.216
Data Source: BioPlex,STRINGDB
FLRT3
Tbio
Novelty: 0.05467656
p_int: 0.999993619
p_ni: 2.34e-7
p_wrong: 0.000006147
Score: 0.204
Data Source: BioPlex,STRINGDB
EPHA7
Tchem
Family: Kinase
Novelty: 0.01065563
p_int: 0.999990485
p_ni: 0.000009515
Data Source: BioPlex
BCS1L
Tbio
Family: Enzyme
Novelty: 0.01764582
p_int: 0.999989836
p_ni: 0.000010164
Data Source: BioPlex
ATP11C
Tbio
Family: Transporter
Novelty: 0.05441047
p_int: 0.999938015
p_ni: 0.000061985
Score: 0.15
Data Source: BioPlex,STRINGDB
VAMP4
Tbio
Novelty: 0.02949854
p_int: 0.999932276
p_ni: 0.000067724
Data Source: BioPlex
BLOC1S3
Tbio
Novelty: 0.08465735
p_int: 0.999896358
p_ni: 0.000004581
p_wrong: 0.000099062
Score: 0.189
Data Source: BioPlex,STRINGDB
GMCL1
Tbio
Novelty: 0.1543762
p_int: 0.999845878
p_ni: 0.00015394
p_wrong: 1.82e-7
Data Source: BioPlex
Publication Statistics
PubMed Score  2.54

PubMed score by year
PubTator Score  0.13

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer