Tbio DCAF15 DDB1- and CUL4-associated factor 15

Protein Summary

Description

May be involved in ubiquitination and degradation through a DBB1-CUL4 E3 protein-ubiquitin ligase.

Uniprot Accession IDs

• Q66K64
• B3KS86
• Q96DW0
• Q9BU31

Gene Name

• DCAF15

Ensembl ID

• ENST00000254337
• ENSP00000254337
• ENSG00000132017

Symbol

• C19orf72
• C19orf72

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cellular component	0.75
histone modification site profile	0.69
disease perturbation	0.62
tissue	0.58
transcription factor perturbation	0.54

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.55   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 2   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.55   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 2   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0