Protein Summary
Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness (By similarity).
- ENST00000322350
- ENSP00000313084
- ENSG00000164318
- ENST00000336740
- ENSP00000337607
- ENST00000354891
- ENSP00000346964
- ENST00000397202
- ENSP00000380385
- ENST00000397210
- ENSP00000380393
- ENST00000506135
- ENSP00000425579
- ENST00000514476
- ENSP00000423228
- AGRINL
- AGRNL
- PIKA
- PIKA
- AGRNL
- AGRINL
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
trait | 1 | ||
gene perturbation | 0.85 | ||
protein domain | 0.85 | ||
cell type or tissue | 0.77 | ||
cell line | 0.76 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 76.21 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 99 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 76.21 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 99 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0