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Tdark
FAM219B
Protein FAM219B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000357635
  • ENSP00000350260
  • ENSG00000178761
  • ENST00000563069
  • ENSP00000457594
  • ENST00000563119
  • ENSP00000454719

Symbol
  • C15orf17
  • C15orf17
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.72
microRNA
0.67
kinase perturbation
0.6
transcription factor binding site profile
0.57
histone modification site profile
0.52


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.11   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 11   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.11   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 11   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (24)
1 – 10 of 24
TRMU
Tbio
Family:  Enzyme
Novelty:  0.01615197
p_int:  0.999999098
p_ni:  8.34e-7
p_wrong:  6.9e-8
Score:  0.507
Data Source:  BioPlex,STRINGDB
DPH2
Tbio
Novelty:  0.04268301
p_int:  0.999702604
p_ni:  0.000262
p_wrong:  0.000035396
Score:  0.228
Data Source:  BioPlex,STRINGDB
ELP3
Tbio
Family:  Epigenetic
Novelty:  0.0166061
p_int:  0.997545432
p_ni:  0.002454568
Score:  0.228
Data Source:  BioPlex,STRINGDB
SPAG9
Tbio
Family:  Enzyme
Novelty:  0.00527315
p_int:  0.969140346
p_ni:  0.030859654
Score:  0.241
Data Source:  BioPlex,STRINGDB
MTCH2
Tbio
Novelty:  0.01794294
p_int:  0.950578434
p_ni:  0.04940922
p_wrong:  0.000012346
Score:  0.188
Data Source:  BioPlex,STRINGDB
ELP2
Tbio
Novelty:  0.03034629
p_int:  0.912592399
p_ni:  0.087407601
Score:  0.309
Data Source:  BioPlex,STRINGDB
C4orf19
Tdark
Novelty:  2.1863624
Score:  0.59
Data Source:  STRINGDB
FAM221A
Tdark
Novelty:  1.40181414
Score:  0.558
Data Source:  STRINGDB
ACBD4
Tdark
Novelty:  0.45760774
Score:  0.532
Data Source:  STRINGDB
KATNBL1
Tdark
Novelty:  1.43589506
Score:  0.51
Data Source:  STRINGDB
GWAS Traits (27)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil percentage of leukocytes
2
2
2
81.6
red blood cell density measurement
1
1
1
80
monocyte count
2
2
2
78.9
monocyte percentage of leukocytes
1
1
1
78.9
creatinine measurement
1
1
1
73.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil percentage of leukocytes
2
81.6
red blood cell density measurement
1
80
monocyte count
2
78.9
monocyte percentage of leukocytes
1
78.9
creatinine measurement
1
73.2
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 219 member B
VGNC:11885
453749
Macaque
family with sequence similarity 219 member B
722132
Mouse
MGI:1925573
78323
Dog
family with sequence similarity 219 member B
611580
Horse
family with sequence similarity 219 member B
VGNC:17860
100062043
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 219 member B
Macaque
family with sequence similarity 219 member B
Mouse
Dog
family with sequence similarity 219 member B
Horse
family with sequence similarity 219 member B
Publication Statistics
PubMed Score 0.11
PubMed score by year