Tbio KRT79 Keratin, type II cytoskeletal 79

Protein Summary

Description

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in skeletal muscle, skin and scalp. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]

Uniprot Accession IDs

• Q5XKE5
• Q6P465
• Q7Z793

Gene Name

• KRT79

Ensembl ID

• ENST00000330553
• ENSP00000328358
• ENSG00000185640

Symbol

• K6L
• KB38
• KRT6L
• K6L
• KRT6L

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell line	0.57
cell type or tissue	0.56
cellular component	0.52
PubMedID	0.44
chemical	0.41

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.54   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 109   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.54   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0