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Tdark
TTC23
Tetratricopeptide repeat protein 23

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000262074
  • ENSP00000262074
  • ENSG00000103852
  • ENST00000394129
  • ENSP00000457901
  • ENST00000394132
  • ENSP00000377690
  • ENST00000394135
  • ENSP00000377692
  • ENST00000459771
  • ENSP00000433162
  • ENST00000558663
  • ENSP00000452923

Symbol
  • HCC-8
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.74
disease perturbation
0.68
transcription factor binding site profile
0.66
tissue sample
0.61
kinase perturbation
0.6


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.95   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 164   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.95   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 164   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
tetratricopeptide repeat domain 23
708530
Mouse
MGI:1914259
67009
Rat
RGD:1310409
308708
Dog
tetratricopeptide repeat domain 23
VGNC:47944
488710
Horse
tetratricopeptide repeat domain 23
VGNC:24616
100055995
Species
Name
OMA
EggNOG
Inparanoid
Macaque
tetratricopeptide repeat domain 23
Mouse
Rat
Dog
tetratricopeptide repeat domain 23
Horse
tetratricopeptide repeat domain 23
Pathways (7)
Items per page:
1 – 5 of 7
Data Source
Name
Explore in Pharos
Explore in Source
WikiPathways
Genes related to primary cilium development (based on CRISPR)
WikiPathways
Genes related to primary cilium development (based on CRISPR)
WikiPathways
Genes related to primary cilium development (based on CRISPR)
WikiPathways
Genes related to primary cilium development (based on CRISPR)
WikiPathways
Intraflagellar transport proteins binding to dynein
Name
Explore in Pharos
Explore in Source
Genes related to primary cilium development (based on CRISPR)
Genes related to primary cilium development (based on CRISPR)
Genes related to primary cilium development (based on CRISPR)
Genes related to primary cilium development (based on CRISPR)
Intraflagellar transport proteins binding to dynein
Protein-Protein Interactions (26)
1 – 10 of 26
RAP1GDS1
Tbio
Family: Enzyme
Novelty: 0.06140479
Score: 0.748
Data Source: STRINGDB
SMPDL3A
Tbio
Family: Enzyme
Novelty: 0.14245461
Score: 0.713
Data Source: STRINGDB
TRAPPC11
Tbio
Novelty: 0.05737444
Score: 0.654
Data Source: STRINGDB
PTPN13
Tchem
Family: Enzyme
Novelty: 0.00434963
Score: 0.651
Data Source: STRINGDB
PUF60
Tbio
Novelty: 0.02667356
Score: 0.649
Data Source: STRINGDB
BTN2A2
Tdark
Novelty: 0.46565474
Score: 0.588
Data Source: STRINGDB
PHKA1
Tbio
Family: Kinase
Novelty: 0.02895127
Score: 0.566
Data Source: STRINGDB
BLMH
Tbio
Family: Enzyme
Novelty: 0.00855614
Score: 0.541
Data Source: STRINGDB
SPAM1
Tbio
Family: Enzyme
Novelty: 0.0041597
Score: 0.541
Data Source: STRINGDB
ERICH3
Tdark
Novelty: 0.38740677
Score: 0.534
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.95

PubMed score by year
PubTator Score  7.69

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer