Tbio PLPP4 Phospholipid phosphatase 4

Protein Summary

Description

Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol.

Uniprot Accession IDs

• Q5VZY2
• A2RU82
• Q08EQ2
• Q0IIP2
• Q495B4
• Q5VZY1

Gene Name

• PLPP4

Ensembl ID

• ENST00000398250
• ENSP00000381302
• ENSG00000203805

Symbol

• DPPL2
• PPAPDC1
• PPAPDC1A
• DPPL2
• PPAPDC1
• PPAPDC1A

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0
biological term	0
cell line	0
cell type or tissue	0
cellular component	0

Protein Classes

PANTHER Classes

Protein / Hydrolase / Pyrophosphatase / Phospholipid Phosphatase 4

Protein / Hydrolase / Phosphatase / Phospholipid Phosphatase 4

DTO Classes

Protein / Enzyme / Hydrolase / Phosphatase / Phospholipid Phosphatase 4

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.75   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 80   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.75   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0