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Tbio
ZMYM4
Zinc finger MYM-type protein 4

Protein Summary
Description
Plays a role in the regulation of cell morphology and cytoskeletal organization.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000314607
  • ENSP00000322915
  • ENSG00000146463

Symbol
  • KIAA0425
  • ZNF262
  • MYM
  • CDIR
  • ZNF262
  • ZNF198L3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.97
histone modification site profile
0.82
drug perturbation
0.71
microRNA
0.63
gene perturbation
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.07   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 99   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.07   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 99   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (68)
CRYAA
Tchem
Novelty:  0.01914081
p_int:  0.996608182
p_ni:  0.003391818
Data Source:  BioPlex
TXNL4B
Tbio
Novelty:  0.00695407
p_int:  0.993446542
p_ni:  0.006553458
Data Source:  BioPlex
ZSCAN5A
Tdark
Family:  TF
Novelty:  2.15267128
p_int:  0.9902545
p_ni:  0.009745499
Score:  0.183
Data Source:  BioPlex,STRINGDB
RHOC
Tbio
Family:  Enzyme
Novelty:  0.00262213
p_int:  0.983936428
p_ni:  0.016063572
Score:  0.165
Data Source:  BioPlex,STRINGDB
SCGN
Tbio
Novelty:  0.01434518
p_int:  0.978678955
p_ni:  0.021321018
p_wrong:  2.7e-8
Score:  0.187
Data Source:  BioPlex,STRINGDB
ZSCAN21
Tbio
Family:  TF
Novelty:  0.18025344
p_int:  0.959741106
p_ni:  0.040258891
p_wrong:  3e-9
Data Source:  BioPlex
PCK2
Tbio
Family:  Kinase
Novelty:  0.0035563
p_int:  0.958132594
p_ni:  0.041867406
Score:  0.178
Data Source:  BioPlex,STRINGDB
ZNF385C
Tdark
Novelty:  2.23931637
p_int:  0.944634781
p_ni:  0.055365216
p_wrong:  4e-9
Data Source:  BioPlex
SHARPIN
Tbio
Novelty:  0.0197352
p_int:  0.915831489
p_ni:  0.084168494
p_wrong:  1.8e-8
Data Source:  BioPlex
CIPC
Tdark
Novelty:  0.02263148
p_int:  0.897610808
p_ni:  0.102388721
p_wrong:  4.71e-7
Score:  0.516
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.5
44.2
1
1
0
1.5
44.2
sex hormone-binding globulin measurement
1
1
1
40.7
wellbeing measurement
1
1
1
28.1
BMI-adjusted waist circumference
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.5
44.2
0
1.5
44.2
sex hormone-binding globulin measurement
1
40.7
wellbeing measurement
1
28.1
BMI-adjusted waist circumference
1
21.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger MYM-type containing 4
VGNC:8133
456740
Macaque
zinc finger MYM-type containing 4
712793
Mouse
MGI:1915035
67785
Rat
RGD:1309545
313598
Dog
zinc finger MYM-type containing 4
VGNC:48648
482484
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger MYM-type containing 4
Macaque
zinc finger MYM-type containing 4
Mouse
Rat
Dog
zinc finger MYM-type containing 4
Publication Statistics
PubMed Score 12.07
PubMed score by year
PubTator Score 3.24
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title