You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
LIPM
Lipase member M

Protein Summary
Description
Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000404743
  • ENSP00000383901
  • ENSG00000173239
  • ENST00000539337
  • ENSP00000440375

Symbol
  • LIPL3
  • LIPL3
  • bA304I5.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.85
trait
0.75
protein domain
0.58
cell line
0.37
disease
0.35


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.11   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 71   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.11   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 71   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
lipase family member M
VGNC:7851
466146
Macaque
lipase family member M
694146
Mouse
MGI:1926003
78753
Rat
RGD:1304912
309528
Dog
lipase family member M
VGNC:42700
610497
Species
Name
OMA
EggNOG
Inparanoid
Chimp
lipase family member M
Macaque
lipase family member M
Mouse
Rat
Dog
lipase family member M
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q5VYY2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Developmental Biology (R-HSA-1266738)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Developmental Biology
Reactome
Formation of the cornified envelope
Reactome
Keratinization
Name
Explore in Pharos
Explore in Source
Developmental Biology
Formation of the cornified envelope
Keratinization
Gene Ontology Terms (6)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Traceable Author Statement (TAS)
Reactome
Protein-Protein Interactions (41)
1 – 10 of 41
LIPE
Tchem
Family:  Enzyme
Novelty:  0.00169872
Score:  0.647
Data Source:  STRINGDB
ANKRD22
Tbio
Novelty:  0.28856283
Score:  0.645
Data Source:  STRINGDB
LDAH
Tbio
Family:  Enzyme
Novelty:  0.0951829
Score:  0.588
Data Source:  STRINGDB
TEX30
Tdark
Novelty:  0.69754742
Score:  0.544
Data Source:  STRINGDB
LIPH
Tbio
Family:  Enzyme
Novelty:  0.00961658
Score:  0.524
Data Source:  STRINGDB
GDAP1L1
Tdark
Novelty:  0.47778991
Score:  0.524
Data Source:  STRINGDB
ABHD13
Tdark
Family:  Enzyme
Novelty:  2.01646617
Score:  0.519
Data Source:  STRINGDB
SLC16A12
Tbio
Family:  Transporter
Novelty:  0.06883837
Score:  0.515
Data Source:  STRINGDB
FAM135A
Tdark
Novelty:  0.61758277
Score:  0.514
Data Source:  STRINGDB
IGSF22
Tdark
Novelty:  2.19850291
Score:  0.51
Data Source:  STRINGDB
Publication Statistics
PubMed Score  9.11

PubMed score by year
PubTator Score  3.34

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer