Tbio NKAIN2 Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2

Protein Summary

Description

This gene encodes a transmembrane protein that interacts with the beta subunit of a sodium/potassium-transporting ATPase. A chromosomal translocation involving this gene is a cause of lymphoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

Uniprot Accession IDs

• Q5VXU1
• Q8IYR4
• Q8TF67
• Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 2

Gene Name

• NKAIN2

Ensembl ID

• ENST00000368416
• ENSP00000357401
• ENSG00000188580
• ENST00000368417
• ENSP00000357402
• ENST00000545433
• ENSP00000437798

Symbol

• FAM77B
• TCBA1
• TCBA
• TCBA1
• FAM77B
• NKAIP2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
trait	1
phenotype	0.8
tissue sample	0.69
histone modification site profile	0.57
cell type or tissue	0.56

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.37   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 65   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.37   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 65   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0