Tdark UBE2U Ubiquitin-conjugating enzyme E2 U

Protein Summary

Description

Catalyzes the covalent attachment of ubiquitin to other proteins.

Uniprot Accession IDs

• Q5VVX9
• Q8N1D4

Gene Name

• UBE2U

Ensembl ID

• ENST00000371076
• ENSP00000360116
• ENSG00000177414
• ENST00000611228
• ENSP00000481174

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.95
gene perturbation	0.93
cellular component	0.61
cell line	0.6
virus perturbation	0.59

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.69   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 138   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.69   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 138   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0