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Tdark
FAM171A1
Protein FAM171A1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000378116
  • ENSP00000367356
  • ENSG00000148468

Symbol
  • C10orf38
  • APCN
  • C10orf38
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.9
transcription factor perturbation
0.88
disease
0.65
PubMedID
0.65
histone modification site profile
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.09   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 51   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.09   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 51   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (33)
1 – 10 of 33
FAM171B
Tdark
Novelty:  0.38456365
p_int:  0.999999834
p_ni:  1.59e-7
p_wrong:  7e-9
Score:  0.345
Data Source:  BioPlex,STRINGDB
PCDHGB1
Tdark
Novelty:  0.60440805
p_int:  0.999982027
p_ni:  0.000008856
p_wrong:  0.000009117
Score:  0.162
Data Source:  BioPlex,STRINGDB
TNFRSF17
Tclin
Novelty:  0.00222663
p_int:  0.999976048
p_ni:  0.000023952
Score:  0.345
Data Source:  BioPlex,STRINGDB
SHANK1
Tbio
Novelty:  0.01475447
Score:  0.706
Data Source:  STRINGDB
RADIL
Tbio
Novelty:  0.08747353
Score:  0.619
Data Source:  STRINGDB
RASIP1
Tbio
Novelty:  0.07135021
Score:  0.586
Data Source:  STRINGDB
C22orf42
Tdark
Novelty:  3.51429983
Score:  0.571
Data Source:  STRINGDB
C12orf29
Tdark
Novelty:  0.50477777
Score:  0.567
Data Source:  STRINGDB
SMG8
Tdark
Novelty:  0.18080965
Score:  0.556
Data Source:  STRINGDB
TOR4A
Tdark
Novelty:  1.44737036
Score:  0.555
Data Source:  STRINGDB
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hip circumference
1
1
1
0.4
1
1
0
1.2
0.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hip circumference
1
0.4
0
1.2
0.3
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 171 member A1
VGNC:3858
450322
Macaque
family with sequence similarity 171 member A1
703843
Mouse
MGI:2442917
269233
Dog
family with sequence similarity 171 member A1
VGNC:40622
607108
Horse
family with sequence similarity 171 member A1
VGNC:17824
100068712
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 171 member A1
Macaque
family with sequence similarity 171 member A1
Mouse
Dog
family with sequence similarity 171 member A1
Horse
family with sequence similarity 171 member A1
Publication Statistics
PubMed Score 3.09
PubMed score by year
PubTator Score 0.28
PubTator score by year