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Tdark
PRPF38B
Pre-mRNA-splicing factor 38B

Protein Summary
Description
May be required for pre-mRNA splicing.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000370022
  • ENSP00000359039
  • ENSG00000134186
  • ENST00000370025
  • ENSP00000359042

Symbol
  • NET1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.91
interacting protein
0.86
ligand (protein) perturbation
0.83
transcription factor binding site profile
0.79
histone modification site profile
0.65


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.27   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 19   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.27   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 19   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
pre-mRNA processing factor 38B
VGNC:1472
737845
Macaque
pre-mRNA processing factor 38B
695835
Mouse
MGI:1914171
66921
Rat
RGD:1562940
499691
Dog
pre-mRNA processing factor 38B
VGNC:45023
613001
Species
Name
OMA
EggNOG
Inparanoid
Chimp
pre-mRNA processing factor 38B
Macaque
pre-mRNA processing factor 38B
Mouse
Rat
Dog
pre-mRNA processing factor 38B
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q5VTL8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (78)
1 – 10 of 78
JMJD6
Tbio
Family: Enzyme
Novelty: 0.00305479
p_int: 0.999999805
p_ni: 1.93e-7
p_wrong: 2e-9
Score: 0.535
Data Source: BioPlex,STRINGDB
LUC7L
Tbio
Novelty: 0.05748021
p_int: 0.999989474
p_ni: 0.000003116
p_wrong: 0.00000741
Score: 0.769
Data Source: BioPlex,STRINGDB
SAP18
Tbio
Family: Enzyme
Novelty: 0.03918373
p_int: 0.999987092
p_ni: 0.000002883
p_wrong: 0.000010025
Data Source: BioPlex
ZC3H18
Tdark
Novelty: 0.3515546
p_int: 0.999972918
p_ni: 0.000026981
p_wrong: 1.01e-7
Score: 0.575
Data Source: BioPlex,STRINGDB
CLK3
Tchem
Family: Kinase
Novelty: 0.03466191
p_int: 0.99990702
p_ni: 0.000077571
p_wrong: 0.000015409
Score: 0.707
Data Source: BioPlex,STRINGDB
PNN
Tbio
Novelty: 0.01395394
Score: 0.868
Data Source: STRINGDB
RBM25
Tbio
Novelty: 0.05557892
Score: 0.864
Data Source: STRINGDB
PRPF38A
Tbio
Novelty: 0.10698531
Score: 0.828
Data Source: STRINGDB
RCC1
Tbio
Novelty: 0.00260884
Score: 0.817
Data Source: STRINGDB
SNRPB2
Tbio
Novelty: 0.17219587
Score: 0.808
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.27

PubMed score by year
PubTator Score  0.33

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer