Tdark WDR78 WD repeat-containing protein 78

Protein Summary

Uniprot Accession IDs

• Q5VTH9
• A8K9W5
• B5MDT3
• H7BY80
• Q5VTI0
• Q8N5G5
• Q9H5R9
• Q9UF44

Gene Name

• WDR78

Ensembl ID

• ENST00000371023
• ENSP00000360062
• ENSG00000152763
• ENST00000371026
• ENSP00000360065

Symbol

• DIC4

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.8
virus perturbation	0.68
disease perturbation	0.62
tissue sample	0.61
transcription factor perturbation	0.61

Protein Classes

PANTHER Classes

Protein / Cytoskeletal Protein / Microtubule Family Cytoskeletal Protein / Wd Repeat-containing Protein 78

DTO Classes

Protein / Cellular Structure / Microtubule Family Cytoskeletal Protein / Wd Repeat-containing Protein 78

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.7   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 17   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.7   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 17   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0