Tbio MINOS1 MICOS complex subunit MIC10

Protein Summary

Description

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.

Uniprot Accession IDs

• Q5TGZ0
• Q96G68

Gene Name

• MINOS1

Ensembl ID

• ENST00000322753
• ENSP00000325562
• ENSG00000173436

Symbol

• C1orf151
• MIC10
• MIO10
• Mic10
• MINOS1
• C1orf151

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
small molecule perturbation	0.92
cell type or tissue	0.86
histone modification site profile	0.77
transcription factor perturbation	0.74
transcription factor	0.68

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.72   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 89   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.72   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 89   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0