You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
HDGFL1
Hepatoma-derived growth factor-like protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000510882
  • ENSP00000442129
  • ENSG00000112273

Symbol
  • PWWP1
  • HRP-1
  • PWWP1
  • Hdgfrp1
  • dJ309H15.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease
0.59
cell line
0.51
cell type or tissue
0.51
biological process
0.49
tissue sample
0.43


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.3   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 89   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.3   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 89   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (17)
POGZ
Tbio
Novelty:  0.03603188
Score:  0.698
Data Source:  STRINGDB
UBQLNL
Tdark
Novelty:  0.48160388
Score:  0.69
Data Source:  STRINGDB
ACTL7A
Tbio
Novelty:  0.14016043
Score:  0.68
Data Source:  STRINGDB
TRIP12
Tbio
Family:  Enzyme
Novelty:  0.03433452
Score:  0.67
Data Source:  STRINGDB
PWWP2B
Tdark
Family:  Epigenetic
Novelty:  2.2483299
Score:  0.67
Data Source:  STRINGDB
ZSWIM6
Tbio
Novelty:  0.20377569
Score:  0.577
Data Source:  STRINGDB
CCIN
Tbio
Novelty:  0.05318622
Score:  0.573
Data Source:  STRINGDB
FTMT
Tbio
Novelty:  0.01843809
Score:  0.557
Data Source:  STRINGDB
TKTL2
Tbio
Family:  Enzyme
Novelty:  0.0915871
Score:  0.542
Data Source:  STRINGDB
KIF2B
Tbio
Novelty:  0.09958244
Score:  0.519
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
6
5
4
1.1
88.7
mean platelet volume
1
1
1
68.6
BMI-adjusted waist circumference
1
1
1
31.4
electrocardiography
1
1
3
31.4
waist circumference
1
1
1
26.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
4
1.1
88.7
mean platelet volume
1
68.6
BMI-adjusted waist circumference
1
31.4
electrocardiography
3
31.4
waist circumference
1
26.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
HDGF like 1
707149
Species
Name
OMA
EggNOG
Inparanoid
Macaque
HDGF like 1
Publication Statistics
PubMed Score 4.30
PubMed score by year
PubTator Score 2.85
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title