Tdark MFSD4B Sodium-dependent glucose transporter 1

Protein Summary

Description

May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney.

Uniprot Accession IDs

• Q5TF39
• A8K9M0
• Q8IYB6
• Q96PW9
• Q9P0D6

Gene Name

• MFSD4B

Ensembl ID

• ENST00000368847
• ENSP00000357840
• ENSG00000173214

Symbol

• KIAA1919
• NAGLT1
• NaGLT1
• KIAA1919

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0
biological term	0
cell line	0
cell type or tissue	0
cellular component	0

Protein Classes

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc60 Glucose Transporters / Sodium-dependent Glucose Transporter 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.32   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 24   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.32   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 24   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0