You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1

Protein Summary
Description
May play an essential role for the assembly of the mitochondrial F1-F0 complex. This gene encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. This protein binds specifically to the F1 beta subunit and is thought to prevent this subunit from forming nonproductive homooligomers during enzyme assembly. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Aug 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000532925
  • ENSP00000435732
  • ENSG00000123472
  • ENST00000542495
  • ENSP00000443588
  • ENST00000574428
  • ENSP00000459167

Symbol
  • ATP11
  • ATP11
  • ATP11p
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.74
histone modification site profile
0.73
tissue
0.69
microRNA
0.62
transcription factor binding site profile
0.6


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.68   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 80   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.68   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (58)
ATP5F1B
Tbio
Family:  Enzyme
Novelty:  0.01053177
p_int:  0.999994358
p_ni:  0.000005642
Score:  0.973
Data Source:  BioPlex,STRINGDB
ERAL1
Tbio
Family:  Enzyme
Novelty:  0.01695998
p_int:  0.951473988
p_ni:  0.048526012
Score:  0.513
Data Source:  BioPlex,STRINGDB
OTC
Tchem
Family:  Enzyme
Novelty:  0.00544004
p_int:  0.894285901
p_ni:  0.105714099
Score:  0.188
Data Source:  BioPlex,STRINGDB
NDUFS7
Tclin
Family:  Enzyme
Novelty:  0.01562198
p_int:  0.807180303
p_ni:  0.192819697
Data Source:  BioPlex
RPUSD3
Tdark
Family:  Enzyme
Novelty:  1.00226099
p_int:  0.793092139
p_ni:  0.206907861
Score:  0.559
Data Source:  BioPlex,STRINGDB
OXCT2
Tbio
Family:  Enzyme
Novelty:  0.08045369
p_int:  0.768361777
p_ni:  0.231638223
Score:  0.216
Data Source:  BioPlex,STRINGDB
YBEY
Tdark
Family:  Enzyme
Novelty:  0.02778029
p_int:  0.760763433
p_ni:  0.239236567
Data Source:  BioPlex
ATPAF2
Tbio
Family:  Enzyme
Novelty:  0.04184643
Score:  0.965
Data Source:  STRINGDB
ATP5F1A
Tbio
Family:  Enzyme
Novelty:  0.01052213
Score:  0.922
Data Source:  STRINGDB
ATP5F1C
Tbio
Family:  Enzyme
Novelty:  0.07666564
Score:  0.829
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
4.3
14.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
4.3
14.2
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2180560
230649
Rat
RGD:1305417
313510
Dog
ATP synthase mitochondrial F1 complex assembly factor 1
VGNC:38290
610408
Horse
ATP synthase mitochondrial F1 complex assembly factor 1
VGNC:15689
100064407
Cow
ATP synthase mitochondrial F1 complex assembly factor 1
VGNC:26332
505430
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
ATP synthase mitochondrial F1 complex assembly factor 1
Horse
ATP synthase mitochondrial F1 complex assembly factor 1
Cow
ATP synthase mitochondrial F1 complex assembly factor 1
Publication Statistics
PubMed Score 24.68
PubMed score by year
PubTator Score 5.10
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title