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Tbio
FRY
Protein furry homolog

Protein Summary
Description
Plays a crucial role in the structural integrity of mitotic centrosomes and in the maintenance of spindle bipolarity by promoting PLK1 activity at the spindle poles in early mitosis. May function as a scaffold promoting the interaction between AURKA and PLK1, thereby enhancing AURKA-mediated PLK1 phosphorylation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000542859
  • ENSP00000445043
  • ENSG00000073910

Symbol
  • C13orf14
  • CG003
  • 13CDNA73
  • 214K23.2
  • C13orf14
  • bA207N4.2
  • bA37E23.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.79
PubMedID
0.78
co-expressed gene
0.72
virus perturbation
0.72
transcription factor binding site profile
0.63


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.48   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 40   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.48   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 40   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0