Tdark UTP14C U3 small nucleolar RNA-associated protein 14 homolog C

Protein Summary

Description

Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis (By similarity).

Uniprot Accession IDs

• Q5TAP6
• Q5FWG3
• Q92555

Gene Name

• UTP14C

Ensembl ID

• ENST00000521776
• ENSP00000428619
• ENSG00000253797

Symbol

• KIAA0266
• UTP14B
• KIAA0266
• 2700066J21Rik

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.75
tissue	0.61
microRNA	0.6
transcription factor perturbation	0.54
PubMedID	0.51

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Nuclease / U3 Small Nucleolar Rna-associated Protein 14 Homolog C

Protein / Nucleic Acid Binding / Rna Binding Protein / Ribosomal Protein / U3 Small Nucleolar Rna-associated Protein 14 Homolog C

DTO Classes

Protein / Enzyme / Nuclease / U3 Small Nucleolar Rna-associated Protein 14 Homolog C

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.31   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 19   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.31   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 19   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0