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Tdark
FAM102A
Protein FAM102A

Protein Summary
Description
May play a role in estrogen action.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000373084
  • ENSP00000362176
  • ENSG00000167106
  • ENST00000373095
  • ENSP00000362187

Symbol
  • C9orf132
  • EEIG1
  • EEIG1
  • SYM-3A
  • C9orf132
  • bA203J24.7
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.95
disease perturbation
0.9
virus perturbation
0.88
microRNA
0.84
transcription factor perturbation
0.84


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.81   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 11   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.81   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 11   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
3
3
3
83.4
myeloid white cell count
1
1
1
7.7
urate measurement
1
1
1
3.6
neutrophil count
1
1
1
2
leukocyte count
1
1
1
1.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
3
83.4
myeloid white cell count
1
7.7
urate measurement
1
3.6
neutrophil count
1
2
leukocyte count
1
1.9
Protein-Protein Interactions (39)
1 – 10 of 39
SERPINB8
Tbio
Novelty: 0.03308357
p_int: 0.978073253
p_ni: 0.021925889
p_wrong: 8.58e-7
Score: 0.39
Data Source: BioPlex,STRINGDB
SKAP1
Tbio
Family: Enzyme
Novelty: 0.03753848
Score: 0.749
Data Source: STRINGDB
WDR44
Tdark
Novelty: 0.02158824
Score: 0.712
Data Source: STRINGDB
SGTB
Tbio
Novelty: 0.03243414
Score: 0.688
Data Source: STRINGDB
EHBP1
Tbio
Novelty: 0.0656858
Score: 0.636
Data Source: STRINGDB
DPM2
Tdark
Novelty: 0.04752556
Score: 0.596
Data Source: STRINGDB
PCMT1
Tbio
Family: Enzyme
Novelty: 0.01414946
Score: 0.553
Data Source: STRINGDB
SIRPB2
Tdark
Novelty: 2.51444012
Score: 0.528
Data Source: STRINGDB
ESR1
Tclin
Family: NR
Novelty: 0.00005938
Score: 0.526
Data Source: STRINGDB
SRMS
Tchem
Family: Kinase
Novelty: 0.22151736
Score: 0.519
Data Source: STRINGDB
Publication Statistics
PubMed Score  3.81

PubMed score by year
PubTator Score  1.34

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer