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Tbio
GPR158
Probable G-protein coupled receptor 158

Protein Summary
Description
Orphan receptor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000376351
  • ENSP00000365529
  • ENSG00000151025

Symbol
  • KIAA1136
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.77
gene perturbation
0.71
phenotype
0.66
histone modification site profile
0.61
interacting protein
0.57


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.06   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 88   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.06   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 88   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
diverticular disease
1
1
0
1.1
93.8
gut microbiome measurement
1
1
0
7.2
78.9
intraocular pressure measurement
2
3
3
65.6
central corneal thickness
1
1
0
1.4
24.3
intelligence
1
1
1
21.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
diverticular disease
0
1.1
93.8
gut microbiome measurement
0
7.2
78.9
intraocular pressure measurement
3
65.6
central corneal thickness
0
1.4
24.3
intelligence
1
21.4
Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (27)
1 – 10 of 27
RGS7
Tbio
Novelty: 0.01643407
Score: 0.764
Data Source: STRINGDB
RGS6
Tbio
Novelty: 0.02200804
Score: 0.664
Data Source: STRINGDB
GPRC6A
Tchem
Family: GPCR
Novelty: 0.01625616
Score: 0.645
Data Source: STRINGDB
KCNJ9
Tbio
Family: IC
Novelty: 0.02279401
Score: 0.635
Data Source: STRINGDB
GPR156
Tdark
Family: GPCR
Novelty: 0.39183023
Score: 0.575
Data Source: STRINGDB
YME1L1
Tbio
Family: Enzyme
Novelty: 0.00180835
Score: 0.575
Data Source: STRINGDB
WAC
Tbio
Novelty: 0.02189388
Score: 0.562
Data Source: STRINGDB
CYSLTR1
Tclin
Family: GPCR
Novelty: 0.00337777
Score: 0.55
Data Source: STRINGDB
GPRC5C
Tbio
Family: GPCR
Novelty: 0.16942353
Score: 0.525
Data Source: STRINGDB
KCNC1
Tclin
Family: IC
Novelty: 0.00252943
Score: 0.525
Data Source: STRINGDB
Publication Statistics
PubMed Score  14.06

PubMed score by year
PubTator Score  4.39

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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