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Tdark
ZNF618
Zinc finger protein 618

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000288466
  • ENSP00000288466
  • ENSG00000157657
  • ENST00000374126
  • ENSP00000363241
  • ENST00000615615
  • ENSP00000483198

Symbol
  • KIAA1952
  • NEDD10
  • FP13169
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.68
microRNA
0.65
phenotype
0.65
cell line
0.57
transcription factor perturbation
0.54


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.94   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 37   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.94   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 37   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
pulse pressure measurement
1
1
1
57.4
balding measurement
1
1
1
47.2
1
1
1
16.8
serum metabolite measurement
1
1
1
16.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
pulse pressure measurement
1
57.4
balding measurement
1
47.2
1
16.8
serum metabolite measurement
1
16.8
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 618
VGNC:4909
742226
Macaque
zinc finger protein 618
708866
Mouse
MGI:1919950
72701
Rat
RGD:1310743
313253
Dog
zinc finger protein 618
VGNC:48776
474809
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 618
Macaque
zinc finger protein 618
Mouse
Rat
Dog
zinc finger protein 618
Protein-Protein Interactions (32)
1 – 10 of 32
CSNK1A1
Tchem
Family: Kinase
Novelty: 0.00636472
p_int: 0.999999974
p_ni: 1.8e-8
p_wrong: 7e-9
Score: 0.358
Data Source: BioPlex,STRINGDB
CSNK1E
Tchem
Family: Kinase
Novelty: 0.00891859
p_int: 0.999999193
p_ni: 8.05e-7
p_wrong: 3e-9
Score: 0.563
Data Source: BioPlex,STRINGDB
CSNK1D
Tchem
Family: Kinase
Novelty: 0.00896935
p_int: 0.999986976
p_ni: 0.000012897
p_wrong: 1.27e-7
Score: 0.588
Data Source: BioPlex,STRINGDB
ZNF576
Tdark
Family: TF
Novelty: 13.18548387
p_int: 0.999981953
p_ni: 0.000018026
p_wrong: 2.1e-8
Score: 0.243
Data Source: BioPlex,STRINGDB
CHD2
Tbio
Family: Epigenetic
Novelty: 0.09602647
Score: 0.727
Data Source: STRINGDB
PANK4
Tbio
Family: Kinase
Novelty: 0.14150809
Score: 0.725
Data Source: STRINGDB
TMEM268
Tdark
Novelty: 4.79855247
Score: 0.678
Data Source: STRINGDB
FARS2
Tchem
Family: Enzyme
Novelty: 0.00771459
Score: 0.618
Data Source: STRINGDB
MBTD1
Tbio
Family: Epigenetic
Novelty: 0.11651052
Score: 0.579
Data Source: STRINGDB
KIF12
Tdark
Novelty: 0.14893428
Score: 0.543
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.94

PubMed score by year
PubTator Score  1.08

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer