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Tbio
LCE1B
Late cornified envelope protein 1B

Protein Summary
Description
Precursors of the cornified envelope of the stratum corneum.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000360090
  • ENSP00000353203
  • ENSG00000196734

Symbol
  • LEP2
  • SPRL2A
  • LEP2
  • SPRL2A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.68
cell line
0.45
biological term
0.33
tissue sample
0.32
protein domain
0.26


Related Tools
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ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.84   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 52   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.84   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 52   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q5T7P3-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Developmental Biology (R-HSA-1266738)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Developmental Biology
Reactome
Formation of the cornified envelope
Reactome
Keratinization
Name
Explore in Pharos
Explore in Source
Developmental Biology
Formation of the cornified envelope
Keratinization
Gene Ontology Terms (6)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (44)
1 – 10 of 44
LCE1A
Tbio
Novelty: 0.04596696
Score: 0.996
Data Source: STRINGDB
LCE1E
Tdark
Novelty: 0.46343337
Score: 0.994
Data Source: STRINGDB
LCE1D
Tbio
Novelty: 0.52901166
Score: 0.991
Data Source: STRINGDB
LCE3C
Tbio
Novelty: 0.04910233
Score: 0.988
Data Source: STRINGDB
LCE3B
Tbio
Novelty: 0.05400263
Score: 0.986
Data Source: STRINGDB
LCE2D
Tdark
Novelty: 1.74927
Score: 0.982
Data Source: STRINGDB
LCE2B
Tdark
Novelty: 0.88335558
Score: 0.98
Data Source: STRINGDB
LCE1F
Tdark
Novelty: 1.56312927
Score: 0.974
Data Source: STRINGDB
LCE6A
Tdark
Novelty: 2.0416597
Score: 0.973
Data Source: STRINGDB
LCE2C
Tdark
Novelty: 4.51851552
Score: 0.968
Data Source: STRINGDB
Publication Statistics
PubMed Score  12.84

PubMed score by year
PubTator Score  10.83

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer