You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
L1TD1
LINE-1 type transposase domain-containing protein 1

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.59   (req: < 5)
Gene RIFs: 11   (req: <= 3)
Antibodies: 74   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.59   (req: >= 5)
Gene RIFs: 11   (req: > 3)
Antibodies: 74   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.1
27.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
27.2
Protein Data Bank (2)
1 – 2 of 2
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (23)
1 – 10 of 23
LIN28A
Tbio
Family: TF
Novelty: 0.00199524
Score: 0.908
Data Source: STRINGDB
DPPA4
Tbio
Novelty: 0.05764302
Score: 0.771
Data Source: STRINGDB
DHX9
Tbio
Family: Enzyme
Novelty: 0.00130907
Score: 0.697
Data Source: STRINGDB
POU5F1
Tbio
Family: TF
Novelty: 0.00033974
Score: 0.621
Data Source: STRINGDB
NANOG
Tbio
Family: TF
Novelty: 0.00054893
Score: 0.612
Data Source: STRINGDB
KANK4
Tdark
Novelty: 0.22871735
Score: 0.561
Data Source: STRINGDB
ZSCAN10
Tdark
Family: TF
Novelty: 0.14279957
Score: 0.551
Data Source: STRINGDB
SALL4
Tbio
Family: TF
Novelty: 0.00354374
Score: 0.546
Data Source: STRINGDB
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.536
Data Source: STRINGDB
DNMT3B
Tchem
Family: Epigenetic
Novelty: 0.00118766
Score: 0.528
Data Source: STRINGDB
Publication Statistics
PubMed Score  9.59

PubMed score by year
PubTator Score  3.64

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer